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Test Code C341Q Complement C3 and C4 with Anti-C1q Antibodies, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Useful For

Evaluating patients with suspected anti-C1q vasculitis

 

Predicting renal involvement in patients with systemic lupus erythematosus

Profile Information

Test ID Reporting Name Available Separately Always Performed
C3 Complement C3, S Yes Yes
C4 Complement C4, S Yes Yes
AC1Q Anti-C1q Antibodies, IgG, S Yes Yes

Method Name

AC1Q: Enzyme-Linked Immunosorbent Assay (ELISA)

C3, C4: Nephelometry

Reporting Name

C3 and C4 with Anti-C1q, IgG, S

Specimen Type

Serum

Specimen Minimum Volume

0.9 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

C3:

75-175 mg/dL

 

C4:

14-40 mg/dL

 

AC1Q:

<20 U/mL (Negative)

20-39 U/mL (Weak Positive)

40-80 U/mL (Moderate Positive)

>80 U/mL (Strong Positive)

Day(s) Performed

C3, C4: Monday through Friday

AC1Q: Wednesday

Report Available

2 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86160 x2

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C341Q C3 and C4 with Anti-C1q, IgG, S In Process

 

Result ID Test Result Name Result LOINC Value
C3 Complement C3, S 4485-9
C4 Complement C4, S 4498-2
AC1Q Anti-C1q Antibodies, IgG, S 44702-9

NY State Approved

Yes