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Test Code CHFXH Chromosome Analysis, Hematologic Disorders, Fixed Cells

Useful For

Assisting in the diagnosis and classification of certain malignant hematological disorders in fixed cells

 

Evaluating the prognosis of patients with certain malignant hematologic disorders

 

Monitoring effects of treatment

 

Monitoring patients in remission

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
_ML20 Metaphases, 1-19 No, (Bill Only) No
_M25 Metaphases, 20-25 No, (Bill Only) No
_MG25 Metaphases, >25 No, (Bill Only) No
_STAC Ag-Nor/CBL Stain No, (Bill Only) No

Testing Algorithm

This test only includes a charge for professional interpretation of results and does not include charges for analysis.

 

Analysis charges will be incurred for total work performed, and generally include 2 banded karyograms and the analysis of 20 or more metaphase cells for this test. If no metaphase cells are available for analysis, no analysis charges will be incurred. If additional analysis work is required, additional charges may be incurred. See the Method Description for specific details.

 

For more information see:

-Acute Promyelocytic Leukemia: Guideline to Diagnosis and Follow-up

-Bone Marrow Staging for Known or Suspected Malignant Lymphoma Algorithm

-Multiple Myeloma: Laboratory Screening

-Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation

Method Name

Chromosome Analysis

Reporting Name

Chromosomes, Hematol Fixed Cells

Specimen Type

Varies


Necessary Information


A pathology and/or flow cytometry report may be requested by the Genomics Laboratory to optimize testing and aid in interpretation of results.

 

Provide a reason for testing and specimen type with each specimen. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed.



Specimen Required


Specimen Volume: 2 mL

Additional Information: Advise Express Mail or equivalent if not on courier service.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Refrigerated 

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

An interpretative report will be provided.

Day(s) Performed

Monday through Friday

Report Available

10 to 11 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88291- Interpretation and report

88264 w/ modifier 52-Chromosome analysis with less than 20 cells (if appropriate)

88264-Chromosome analysis with 20 to 25 cells (if appropriate)

88264, 88285-Chromosome analysis with greater than 25 cells (if appropriate)

88283-Additional specialized banding technique (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CHFXH Chromosomes, Hematol Fixed Cells In Process

 

Result ID Test Result Name Result LOINC Value
38487 Result Summary 50397-9
38488 Interpretation 69965-2
38489 Result 62356-1
38490 Reason for Referral 42349-1
38491 Specimen 31208-2
38492 Source 31208-2
38493 Method 85069-3
38494 Banding Method 62359-5
38495 Additional Information 48767-8
38496 Released By 18771-6

NY State Approved

Yes