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Test Code COKEM Cocaine and Metabolites Confirmation, Meconium

Reporting Name

Cocaine and Metabolites, Confirm, M

Useful For

Detecting in utero drug exposure up to 5 months before birth

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order COKMX / Cocaine and Metabolite Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen (preferred) 21 days
  Refrigerated  21 days
  Ambient  72 hours

Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers		 Reject

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) result.

Cutoff concentrations for LC-MS/MS testing:

Cocaine: 20 ng/g

Benzoylecgonine: 20 ng/g

Cocaethylene: 20 ng/g

m-Hydroxybenzoylecgonine: 20 ng/g

Day(s) Performed

Monday through Sunday

CPT Code Information

80353

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
COKEM Cocaine and Metabolites, Confirm, M 69008-1

 

Result ID Test Result Name Result LOINC Value
31859 Cocaine 69009-9
31860 Benzoylecgonine 69010-7
31861 Cocaethylene 69011-5
31862 m-Hydroxybenzoylecgonine 69012-3
31864 Interpretation 69050-3
31865 Chain of Custody 77202-0

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 3 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.