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Test Code CORAB Hepatitis B Virus Core Total Antibodies, with Reflex to Hepatitis B Virus Core IgM Antibody, Serum

Reporting Name

HBc Total Ab, w/Reflex, S

Useful For

Detection and differentiation between recent, past/resolved, or chronic hepatitis B

 

Diagnosis of recent hepatitis B virus (HBV) infection during the "window period" when both hepatitis B surface (HBs) antigen and anti-HBs are negative

 

This test is not useful for determining immunity to or recovery from HBV infection.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HBIM HBc IgM Ab, S Yes No

Testing Algorithm

If the hepatitis B virus core (HBc) total antibodies test result is positive, then anti-HBc IgM is performed at an additional charge.

Method Name

Electrochemiluminescence Immunoassay (ECLIA)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum SST


Necessary Information


Date of collection is required.



Specimen Required


Patient Preparation: For 24 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Serum gel (red-top tubes are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.7 mL

Collection Instructions:

1. Centrifuge blood collection tube per manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into a plastic vial.


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 90 days
  Refrigerated  6 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Special Instructions

Reference Values

Negative

Interpretation depends on clinical setting.

 

See Viral Hepatitis Serologic Profiles

Day(s) Performed

Monday through Saturday

CPT Code Information

86704

86705 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CORAB HBc Total Ab, w/Reflex, S 13952-7

 

Result ID Test Result Name Result LOINC Value
CORAB HBc Total Ab, w/Reflex, S 13952-7

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

1 to 3 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send 1 of the following:

-Gastroenterology and Hepatology Test Request (T728)

-Infectious Disease Serology Test Request (T916)