Test Code CRTHS Double-Stranded DNA (dsDNA) IgG Antibodies, Crithidia luciliae Immunofluorescence Screen, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL Serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Evaluation and management of anti-double-stranded DNA IgG antibodies in patients with clinical features of systemic lupus erythematosus (SLE) or at-risk for disease
This test should not be used independently for the diagnosis and management of patients with SLE.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CRTHT | dsDNA Ab IFA Titer, IgG, S | No | No |
Testing Algorithm
If the double-stranded DNA (dsDNA) IgG antibodies Crithidia luciliae immunofluorescence screen is positive, then the dsDNA IgG antibodies Crithidia luciliae immunofluorescence titer will be performed at an additional charge.
Method Name
CRTHS, CRTHT: Indirect Immunofluorescence Assay (IFA)
Reporting Name
dsDNA Ab IFA Screen, IgG, SSpecimen Type
SerumSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated | Reject |
Reference Values
DOUBLE-STRANDED DNA (dsDNA) IgG ANTIBODIES, CRITHIDIA LUCILIAE IMMUNOFLUORESCENCE SCREEN
Negative (<1:10)
Reference values apply to all ages.
DOUBLE-STRANDED DNA (dsDNA) IgG ANTIBODIES, CRITHIDIA LUCILIAE IMMUNOFLUORESCENCE TITER
Negative (<1:10)
Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86255
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CRTHS | dsDNA Ab IFA Screen, IgG, S | 6457-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623426 | dsDNA Ab IFA Screen, IgG, S | 6457-6 |
| 623463 | dsDNA Interpretation | 69048-7 |