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HelpTest Code DIG Digoxin Level
Performing Location
Specimen Collection Information
| Specimen | Min. Test Volume | Collection Container | Special Handling |
|---|---|---|---|
| Blood | 0.1 mL | Light Green (lith. heparin) top Gold top Marble Red top |
Reference Ranges & Critical Values
| Assay | Gender | Age Range | Normal Range | Critical Values | Units |
|---|---|---|---|---|---|
| DIG | ALL | 0 Minutes – 150 Years | 0.6 - 1.2 | > 2.0 | ng/mL |
Specimen Stability
24 hours at 2-8°C
Result Interpretation
A relationship between serum levels of digoxin and therapeutic or toxic effects has been demonstrated in numerous studies. Therapeautic effects are seen with concentrations between approximately 0.8 and 2.0 ng/mL. Serum digoxin concentrations above 2.0 ng/mL are associated with symptoms of toxicity, while concentrations less than 0.8 ng/mL are generally not effective. Based on actual new ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure, 2008,a therapeutioc concentration range for digoxin of 0.6 - 1.2 ng/mL is recommended. Increased risk of mortality was observed for digoxin concentration of 1.2 ng/mL and higher.
Day(s) Performed
Monday - Sunday
Special Handling
Note special drawing times:
- Steady State: 1 to 2 weeks (prolonged by renal dysfuntion)
- Post distribution phase: draw at least six (6) hours after the dose.
CPT
80162
LOINC
10535-3