Ordering Guidance

If ordering for diagnostic purposes: order PATHC / Pathology Consultation and then request the stains.

For specimens such as intestine, liver, colon, which do not contain metastatic adenocarcinoma from the stomach or esophagus, order H2BR / HER2 Amplification, Miscellaneous Tumor, FISH, Tissue.

For breast cancer specimens, order HERBA / HER2, Breast, Quantitative Immunohistochemistry, Automated with HER2 FISH Reflex or HERBN / HER2, Breast, Quantitative Immunohistochemistry, Automated, No Reflex.

Shipping Instructions

Attach the green pathology address label included in the kit to the outside of the transport container.

Ship ambient.

Necessary Information

Include accompanying pathology report stating the final diagnosis. If not available, a preliminary diagnosis is acceptable only if it refers to invasive or metastatic gastric or esophageal adenocarcinoma.

Specimen Required

Only formalin-fixed, paraffin-embedded (FFPE) gastric or esophageal adenocarcinoma specimens will be accepted. Fixation in 10% neutral-buffered formalin is preferred. The performance and quality of immunohistochemical stains in 10% neutral-buffered FFPE tissue depends on proper fixation. It is recommended (not required) for surgical specimens to be fixed between 18 and 24 hours and biopsy specimens between 6 and 8 hours.

If being ordered for prognostic purposes:

Specimen Type: Gastric or esophageal adenocarcinoma

Supplies: Pathology Packaging Kit (T554)

Preferred: Paraffin-embedded tissue block containing invasive gastric or esophageal adenocarcinoma tissue

Additional Information: Paraffin blocks will be returned with final report.

Acceptable: Slides

Specimen Volume: 5

Collection Instructions: 5 Unstained sections, containing gastric or esophageal adenocarcinoma, on charged slides cut at 4 microns less than 1 month ago.