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Test Code LEFLU Leflunomide Metabolite (Teriflunomide), Serum

Reporting Name

Leflunomide Metabolite, S

Useful For

Therapeutic monitoring of patients actively taking leflunomide

 

Assessment of elimination in patients requiring enhanced elimination of the drug

Method Name

High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood no sooner than 12 hours (trough value) after last dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Ambient (preferred) 28 days
  Frozen  28 days
  Refrigerated  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Therapeutic: >40 mcg/mL

Elimination: <0.020 mcg/mL

Day(s) Performed

Monday, Wednesday, Friday

CPT Code Information

80193

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LEFLU Leflunomide Metabolite, S 44828-2

 

Result ID Test Result Name Result LOINC Value
60292 Leflunomide Metabolite, S 44828-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

3 to 5 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.