Test Code MANN Alpha-Mannosidase, Leukocytes
Reporting Name
Alpha-Mannosidase, LeukocytesUseful For
Diagnosis of alpha-mannosidosis
This test is not useful for establishing carrier status for alpha-mannosidosis.
Method Name
Fluorometric
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
Whole Blood ACDOrdering Guidance
If clinically suspicious of an oligosaccharidosis, a screening test is available. Order OLIGU / Oligosaccharide Screen, Random, Urine.
Shipping Instructions
For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerate within 6 days of collection to be stabilized. Collect specimen Monday through Thursday only and not the day before a holiday. Specimen should be collected and packaged as close to shipping time as possible.
Specimen Required
Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Yellow top (ACD solution A)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not aliquot.
Specimen Minimum Volume
5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD | Refrigerated (preferred) | 6 days | YELLOW TOP/ACD |
Ambient | 6 days | YELLOW TOP/ACD |
Reject Due To
Gross hemolysis | Reject |
Special Instructions
Reference Values
≥0.54 nmol/min/mg protein
Day(s) Performed
Preanalytical processing: Monday through Saturday
Assay performed: Once per month
CPT Code Information
82657
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
MANN | Alpha-Mannosidase, Leukocytes | 24053-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
35639 | Alpha-Mannosidase, Leukocytes | 24053-1 |
35640 | Interpretation (MANN) | 59462-2 |
35641 | Reviewed By | 18771-6 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
30 to 45 daysNY State Approved
YesForms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Biochemical Genetics Patient Information (T602)
3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.