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HelpTest Code OPATX Opiates Confirmation, Chain of Custody, Random, Urine
Useful For
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was always under the control of personnel involved with testing the specimen; this control implies that the opportunity for specimen tampering would be limited.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
| ADLTX | Adulterants Survey, CoC, U | Yes | Yes |
Testing Algorithm
Adulterants testing will be performed on all chain of custody urine samples as per regulatory requirements.
Reporting Name
Opiate Confirmation, CoC, USpecimen Type
UrineSpecimen Required
Supplies: Chain of Custody Kit (T282)
Container/Tube: Chain of custody kit containing the specimen containers, seals, and documentation is required.
Specimen Volume: 5 mL
Collection Instructions: Collect urine specimen in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Additional Information: Submitting less than 5 mL will compromise our ability to perform all necessary testing.
Specimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Reference Values
Negative
Cutoff concentrations:
IMMUNOASSAY SCREEN
300 ng/mL
Liquid chromatography tandem mass spectroscopy:
Codeine: 25 ng/mL
Dihydrocodeine: 25 ng/mL
Hydrocodone: 25 ng/mL
Norhydrocodone: 25 ng/mL
Hydromorphone: 25 ng/mL
Oxycodone: 25 ng/mL
Noroxycodone: 25 ng/mL
Oxymorphone: 25 ng/mL
Noroxymorphone: 25 ng/mL
Naloxone: 25 ng/mL
Morphine: 25 ng/mL
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80361
80365
80362
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| OPATX | Opiate Confirmation, CoC, U | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 6541 | Opiates Immunoassay Screen | 70151-6 |
| 36213 | Codeine-by LC-MS/MS | 16250-3 |
| 42005 | Dihydrocodeine-by LC-MS/MS | 19448-0 |
| 36214 | Hydrocodone-by LC-MS/MS | 16252-9 |
| 42006 | Norhydrocodone-by LC-MS/MS | 61422-2 |
| 36215 | Hydromorphone-by LC-MS/MS | 16998-7 |
| 36216 | Oxycodone-by LC-MS/MS | 16249-5 |
| 42007 | Noroxycodone-by LC-MS/MS | 61425-5 |
| 36212 | Oxymorphone-by LC-MS/MS | 17395-5 |
| 42008 | Noroxymorphone-by LC-MS/MS | 90894-7 |
| 42009 | Naloxone-by LC-MS/MS | 77207-9 |
| 36217 | Morphine-by LC-MS/MS | 16251-1 |
| 36218 | Opiates Interpretation | 69050-3 |
| 36219 | Chain of Custody | 77202-0 |
NY State Approved
YesMethod Name
Immunoassay/ Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.