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Test Code VLTS Volatile Screen, Serum

Reporting Name

Volatile Scrn, S

Useful For

Detection and quantitation of acetone, methanol, isopropanol, and ethanol in serum

 

Quantification of the concentration of ethanol in serum correlates with degree of intoxication

 

Evaluation of toxicity to the measured volatile substances

Testing Algorithm

This test includes analysis for methanol, ethanol, isopropanol, and acetone.

Method Name

Headspace Gas Chromatography Flame Ionization Detector (HSGC-FID)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Additional Testing Requirements


If measurement of ethylene glycol is also needed, order ETGL / Ethylene Glycol, Serum in addition to this test.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial for serum collected in red-top tubes only.

Specimen Volume: Full tube

Collection Instructions:

1. Do not use alcohol to clean arm. Use alternative such as Betadine to cleanse arm before collecting any specimen for volatile testing.

2. Avoid exposure of specimen to atmosphere.

3. Centrifuge serum gel tubes with 2 hours of collection but do not aliquot.

4. Centrifuge red-top tubes and aliquot serum in plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Reference Values

Methanol:

Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL

 

Ethanol:

Not detected (Positive results are quantitated.)

Toxic concentration: ≥400 mg/dL

 

Isopropanol:

Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL

 

Acetone:

Not detected (Positive results are quantitated.)

Toxic concentration: ≥10 mg/dL

Day(s) Performed

Monday through Saturday

CPT Code Information

80320

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VLTS Volatile Scrn, S 50025-6

 

Result ID Test Result Name Result LOINC Value
8632 Volatile Scrn, S 32044-0
30917 Methanol, S 5693-7
30918 Ethanol, S 5643-2
30919 Acetone, S 5568-1
30920 Isopropanol, S 5669-7
34376 Chain of Custody 77202-0

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

1 to 2 days

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.